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KERATOMA is a benign tumor
that consists
of keratinocytes
(surface cells of the epidermis) that form the stratum corneum of the skin. A keratoma
is an
excrescence, a spot with
a crust, a plaque, or
a node. Pathology can
occur on
the face, head, back,
arms and
legs. Benign
formations are localized only
on the skin. In
most cases,
keratoma is a single
one. Multiple
pathology is called if
more than 3 growths
form in a small
area. Keratoma
most often occurs in women
and men
over 40
years of age. Causes
of keratomas:
age-related cellular changes;
hormonal and metabolic
disorders; excessive exposure
to ultraviolet rays and
chemical compounds; genetic
predisposition; prolonged use of antibiotics; lack of vitamins
of group A; constant
pressure on the skin
(uncomfortable underwear or
clothing).
The skin epithelium is
structurally multilayered, keratinizing, and the cells
forming it are called
keratinocytes. The multilayered keratinizing epithelium consists
of several
layers of cells lying
on top of each other. Moreover,
the cells of the outer layer
located on the surface
gradually die off,
turning into horny
scales that peel
off and are removed from
the surface of the skin when
washing. When the scales
peel off, new
epithelial cells rise
in their
place from
deeper layers, which
themselves begin to die
off after a while
and turn
into scales.
Thus, there
is a process of constant renewal
of skin epithelial cells
– the surface
ones die and peel
off, and
others that were previously in
the underlying
layer take
their place.
On the basement membrane
of the epithelium, in turn,
new epithelial
cells are constantly forming,
which gradually
move towards
the surface to eventually
become scales and
peel off. Normally, the
rate of
formation of new cells
on the basement membrane
and peeling
of horny scales is balanced.
That is,
only the
number of cells that
are needed to replace
those that have turned into horny
scales is formed again.
If the processes of exfoliation of scales and
the formation of new epithelial
cells are not balanced,
this leads
to the development of various skin
diseases. This is
how they are formed. Keratoma
is formed from unchanged
skin epithelial
cells prone
to excessive
keratinization. That is,
the tumor consists of
a large number of ordinary
keratinocytes – exactly
the same
cells that
form the
normal layers of the epithelium. Since
keratomas are formed from
normal cells, they
are classified as benign tumors.
However, keratomas are prone to
degeneration into cancer.
According to statistics, keratoma malignancy occurs
in 8-20%
of cases, depending on
the type of tumor, the general
condition of the human body,
as well
as the presence of negative factors
contributing to the formation of cancer cells.
Any keratoma
at the initial stage
looks like
a slightly protruding spot
above the skin, colored
in gray
or coffee
colors. The surface of keratomas,
as a rule,
flakes off, which
occurs due to the
formation and peeling
of a large number of horny
scales. As the keratoma develops, the area of the keratoma
increases, and the spot
begins to protrude more strongly above
the surface of the skin. On
sufficiently large keratomas,
a dense
crust of
horny scales
forms, which can
be torn off accidentally or intentionally.
When a keratoma is traumatized,
it can
bleed and
hurt, causing
unpleasant sensations to a person.
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